Package: immuneSIM
Type: Package
Title: Tunable Simulation of B- And T-Cell Receptor Repertoires
Version: 0.8.7
Authors@R: c(
    person("Cédric R.", "Weber", email = "cedric.weber@bsse.ethz.ch",role = c("aut", "cre")),
    person("Victor", "Greiff", email = "victor.greiff@medisin.uio.no",role = "aut"))
Author: Cédric R. Weber [aut, cre],
  Victor Greiff [aut]
Maintainer: Cédric R. Weber <cedric.weber@bsse.ethz.ch>
Description: Simulate full B-cell and T-cell receptor repertoires using an in silico 
    recombination process that includes a wide variety of tunable parameters to introduce noise and biases. 
    Additional post-simulation modification functions allow the user to implant motifs or codon biases as 
    well as remodeling sequence similarity architecture. The output repertoires contain records of all 
    relevant repertoire dimensions and can be analyzed using provided repertoire analysis functions.
    Preprint is available at bioRxiv (Weber et al., 2019 <doi:10.1101/759795>).
Depends: R (>= 3.4.0)
Imports: poweRlaw, stringdist, Biostrings, igraph, stringr, data.table,
        plyr, reshape2, ggplot2, grid, ggthemes, RColorBrewer, Metrics,
        repmis
License: GPL-3
URL: https://immuneSIM.readthedocs.io
BugReports: https://github.com/GreiffLab/immuneSIM/issues
Encoding: UTF-8
LazyData: true
RoxygenNote: 6.1.1
NeedsCompilation: no
Packaged: 2019-09-20 08:43:33 UTC; ceweber
Repository: CRAN
Date/Publication: 2019-09-27 10:30:06 UTC
Built: R 4.1.0; ; 2021-05-27 20:35:16 UTC; unix
